產(chǎn)品介紹

ATP競爭性強效ARK-1抑制劑;an ATP-competitive potent inhibitor of ARK-1;極光激酶抑制劑III是一種有效的ATP競爭性極光相關(guān)激酶（也稱為ARK）抑制劑。Aurora激酶抑制劑III是一種可透過細(xì)胞的2,4-二苯并嘧啶類化合物，已用于研究多種腫瘤類型。在c-myc驅(qū)動的B細(xì)胞淋巴瘤中，小鼠和人類的Aurora激酶蛋白水平均升高；抑制Aurora激酶蛋白的研究可能會導(dǎo)致惡性腫瘤的潛在治療。;Aurora kinase inhibitor III is a potent ATP-competitive aurora related kinase (also designated ARK) inhibitor. Aurora kinase inhibitor III is a cell-permeable, 2,4-dianilinopyrimidine compound which has been used to study a variety of tumor types. Aurora kinase protein levels are elevated in c-myc-driven B-cell lymphomas in both mice and humans; study of the inhibition of Aurora kinase proteins could lead to potential treatments for malignancies.