| 產(chǎn)品描述： | Tegobuvir is a specific, covalent inhibitor of the HCV NS5B polymerase. |
| 靶點(diǎn)： |
HCV;HCVProtease |
| 參考文獻(xiàn)： |
1. Bae AS, et al. Allele-specific real-time PCR system for detection of subpopulations of genotype 1a and 1b hepatitis C NS5B Y448H mutant viruses in clinical samples. J Clin Microbiol. 2011 Sep;49(9):3168-74. 2. Hebner CM, et al. The HCV non-nucleoside inhibitor Tegobuvir utilizes a novel mechanism of action to inhibit NS5B polymerase function. PLoS One. 2012;7(6):e39163. 3. Wong KA, et al. Tegobuvir (GS-9190) potency against HCV chimeric replicons derived from consensus NS5B sequences from genotypes 2b, 3a, 4a, 5a, and 6a. Virology. 2012 Jul 20;429(1):57-62. |
| 溶解性： |
DMSO : ≥ 50 mg/mL (96.64 mM) |
| 保存條件： |
-20℃ |
| 配置溶液濃度參考： |
|
1mg |
5mg |
10mg |
| 1 mM |
1.933 ml |
9.664 ml |
19.327 ml |
| 5 mM |
0.387 ml |
1.933 ml |
3.865 ml |
| 10 mM |
0.193 ml |
0.966 ml |
1.933 ml |
| 50 mM |
0.039 ml |
0.193 ml |
0.387 ml |
|
| 注意： |
部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶(hù)參考交流研究之用。 |
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