乙酰水楊酸

    
分析標準品,HPLC≥98%

Acetylsalicylic acid

源葉
B21505 一鍵復制產(chǎn)品信息
50-78-2
C9H8O4
180.16
MFCD00002430
2-乙酸基苯甲酸,阿司匹林,乙?;?醋柳酸,鄰醋酸基苯甲酸,鄰乙?;畻钏?/b>
貨號 規(guī)格 價格 上海 北京 武漢 南京 購買數(shù)量
B21505-20mg 分析標準品,HPLC≥98% ¥90.00 >10 1 1 1
B21505-200mg 分析標準品,HPLC≥98% ¥350.00 >10 1 - -
B21505-1g 分析標準品,HPLC≥98% ¥1150.00 >10 - - -

產(chǎn)品介紹

 Aspirin (Acetylsalicylic Acid) 是一種口服有效的不可逆的環(huán)氧合酶COX-1 和 COX-2抑制劑,IC50 分別為 5 和 210 μg/mL. Aspirin 誘導細胞凋亡 (apoptosis)。Aspirin 可抑制 NF-κB 的活化。Aspirin 還抑制血小板前列腺素合成酶 (prostaglandin synthetase),可預防冠狀動脈和腦血管血栓形成。

熔點: 134-136°C(lit.)
沸點: 272.96°C
外觀: 白色粉末或結(jié)晶
溶解性: DMSO  :  400  mg/mL  (2220.25  mM;  Need  ultrasonic)

H2O  :  0.1  mg/mL  (0.56  mM;  Need  ultrasonic)
敏感性: 易吸潮
儲存條件: 2-8℃
注意: 部分產(chǎn)品我司僅能提供部分信息,我司不保證所提供信息的權(quán)威性,僅供客戶參考交流研究之用。

參考文獻(28篇)

23. [IF=3.8] Rongbosen Yue et al."The material basis and potential pathways of liver glucose metabolism regulation in Chongqing Tuocha: Insights from molecular dynamics and cell experiments."Journal of Functional Foods.2024 Jul;118:106271 22. [IF=1.8] Jingyi Jin et al."Development and validation of a liquid chromatography–tandem mass spectrometry method for simultaneous quantification of eight Xiakucao Oral liquid–related compounds in rat plasma and its application in pharmacokinetic study."BIOMEDICAL 21. [IF=2.5] Li Xidong et al."Purification and Characterization of a Novel Anticoagulant Peptide from Protein Hydrolysate of Eupolyphaga sinensis Walker."International Journal of Peptide Research and Therapeutics".2024 Mar;30(2):1-15 20. [IF=5.4] Yueying Zhao et al."Chemical components with antibacterial properties found in sanchen powder from traditional Tibetan medicine."JOURNAL OF ETHNOPHARMACOLOGY".2024 May;326:117981 19. [IF=7.3] Mao Jinqian et al."Corilagin alleviates atherosclerosis by inhibiting NLRP3 inflammasome activation via the Olfr2 signaling pathway in vitro and in vivo."Frontiers in Immunology".2024 May;15: 18. [IF=7.5] Hongbo Teng et al."Design and synthesis of 3,4-seco-lupane triterpene derivatives to resist myocardial ischemia-reperfusion injury by inhibiting oxidative stress-mediated mitochondrial dysfunction via the PI3K/AKT/HIF-1α axis."BIOMEDICINE & PHARMACOTHERAPY 17. [IF=1.885] Cao Weiyi et al."Simultaneous Quantification of Aspirin, Its Metabolite Salicylic Acid, and Salvianolic Acid B in Human Plasma Using UPLC-MS/MS."Int J Anal Chem. 2021;2021:6620868 16. [IF=3.24] Jianhua Deng et al."Comparison of analgesic activities of aconitine in different mice pain models."Plos One. 2021 Apr;16(4):e0249276 15. [IF=4.073] Qingchi Wang et al."Proteoglycan from Bacillus sp. BS11 Inhibits the Inflammatory Response by Suppressing the MAPK and NF-κB Pathways in Lipopolysaccharide-Induced RAW264.7 Macrophages."Mar Drugs. 2020 Dec;18(12):585 14. [IF=4.113] Fengyang Li et al."Pretreatment of Indobufen and Aspirin and their Combinations with Clopidogrel or Ticagrelor Alleviates Inflammasome Mediated Pyroptosis Via Inhibiting NF-κB/NLRP3 Pathway in Ischemic Stroke."J Neuroimmune Pharm. 2021 Jan 29 13. [IF=4.142] Wang Huai-Song et al."Anti-cancer adjuvant drug screening via epithelial-mesenchymal transition-related aptamer probe."Anal Bioanal Chem. 2021 Nov;413(28):6951-6962 12. [IF=6.529] Weiyi Cao et al."Drug-drug interactions between salvianolate injection and aspirin based on their metabolic enzymes."Biomed Pharmacother. 2021 Mar;135:111203 11. [IF=6.922] Yucui Jiang et al."P2X7R in Mast Cells is a Potential Target for Salicylic Acid and Aspirin in Treatment of Inflammatory Pain."J Inflamm Res. 2021; 14: 2913–2931 10. [IF=7.46] Xiaoyu Yang et al."Molecularly imprinted polymers and PEG double engineered perovskite: an efficient platform for constructing aqueous solution feasible photoelectrochemical sensor."Sensor Actuat B-Chem. 2020 Feb;304:127321 9. [IF=5.047] Fushi Wang et al."Preparation and functionalization of acetylsalicylic acid loaded chitosan/gelatin membranes from ethanol-based suspensions via electrophoretic deposition."J Mater Chem B. 2018 Apr;6(15):2304-2314 8. Deng, Junlin, et al. "Comparative evaluation of maceration and ultrasonic-assisted extraction of phenolic compounds from fresh olives." Ultrasonics Sonochemistry 37 (2017): 328-334.https://doi.org/10.1016/j.ultsonch.2017.01.023 7. Mengqiu Lu, Haizhen Liang, Pengfei Tu, Yong Jiang. Pharmacodynamic comparison of two different source plants of Murrayae Folium et Cacumen[J]. Journal of Chinese Pharmaceutical Sciences, 2021, 30(1): 49-57.DOI: 10.5246/jcps.2021.01.005 6. Cao, Weiyi, et al. "Simultaneous Quantification of Aspirin, Its Metabolite Salicylic Acid, and Salvianolic Acid B in Human Plasma Using UPLC-MS/MS." International Journal of Analytical Chemistry 2021 (2021). 5. Xiaoyu Yang, Lu Chen, Xiuxiu Xiong, Yun Shu, Dangqin Jin, Yang Zang, Wei Wang, Qin Xu, Xiao-Ya Hu, Molecularly imprinted polymers and PEG double engineered perovskite: an efficient platform for constructing aqueous solution feasible photoelectrochemical se 4. 蘇艷鳳 陳新慧 李萌 等. 副干酪乳桿菌的發(fā)酵條件優(yōu)化及其發(fā)酵液功效評價[J]. 日用化學工業(yè) 2020 v.50;No.334(06):49-54+73. 3. 余麗麗, 范濤, 楊黎燕,等. 明膠微球載藥及其體外釋放性能研究[J]. 化工科技, 2012(06):11-14. 2. 姜亞彤 李明雪 高瑞昶. 乳化液膜法提取廢水中的阿司匹林[J]. 化工進展 2018 37(4): 1559-1565. 1. 魏立琴 王東升 苗小樓 等. 丹翹灌注液抗炎鎮(zhèn)痛作用的研究[J]. 中國農(nóng)學通報 2015(2):75-79.

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